Dr. Guillermo Padilla founded his East Downtown Clinic location @ 2502 Canal St in 1959 after he fell in love with the location.  He established the office and worked there with his son Dr. William Padilla and his Daughter (a Pharmacist), who eventually opened the Canal Street Pharmacy on location.  The Clinic was expanded over the years and has been a center for wellness for many generations of families in the East Downtown area.  The Clinic is situated one block from the METRORail in the East End District and several bus routes for those who enjoy utilizing the various transit systems.  This historic location is within 5 min from Minute Maid Park, Toyota Center, BBVA Stadium, The Original Ninfa’s, East End Farmers Market, and Our Lady of Guadalupe Catholic Church.  Pulse / Padilla clinic accepts most insurance plans but has a wonderful cash pay option for those not currently in a plan.  Most of the Staff and Providers speak Spanish for those who feel more comfortable communicating that way.  You will find staff who really love where they work, many of whom call EaDo home.  Pulse Healthcare System has added new modalities of care and access to Multi-Specialty Doctors to bring even more services to the community.  We hope you will agree that heritage like this is something extraordinary.  This Clinic is open every day of the week and accepts walk-in.  We desire to see your entire family for all your medical needs.  Welcome to Pulse / Padilla Clinic EaDo.


2502 Canal St.
Houston, TX 77003


Phone: 713.224.0555
Fax: 281.894.0426

Most Insurances Accepted

Please call us to verify your insurance plan prior to your appointment.


Video visits let you see your provider from the comfort of your home, making it easier than ever to get the care you need.


We offer complete laboratory services for your convenience.


• Cardiology
• Family Medicine
• Geriatrics
• Internal Medicine
• Podiatry

Diagnostic Imaging

• Ultrasound



Patient Billing

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Patient Portal

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